Objectives: Major adverse cardiac events (MACE) of acute coronary syndrome (ACS) often occur suddenly resulting in high mortality and morbidity. Recently, the rapid development of electronic medical records (EMR) provides the opportunity to utilize the potential of EMR to improve the performance of MACE prediction.
What does Mace mean in cardiology?
Study Definition
Major adverse cardiac events (MACE) were defined as the composite of total death; MI; stroke, hospitalization because of HF; and revascularization, including percutaneous coronary intervention, and coronary artery bypass graft.
What are the 3 types of ACS?
The term acute coronary syndrome (ACS) is applied to patients in whom there is a suspicion or confirmation of acute myocardial ischemia or infarction. Non-ST-elevation myocardial infarction (NSTEMI), ST-elevation MI (STEMI), and unstable angina are the three traditional types of ACS.
What is ACS meaning?
Acute coronary syndrome is a term used to describe a range of conditions associated with sudden, reduced blood flow to the heart. One such condition is a heart attack (myocardial infarction) — when cell death results in damaged or destroyed heart tissue.
What is MACE rate?
The current literature review concluded that MACE remains one of the strongest adverse outcomes in STEMI patients. The incidence of MACE ranges from 4.2% to 51% irrespective of the mode of treatment, with follow-up visits ranging from day 0 to 10 years following STEMI.
What does 3-point MACE mean?
The so-called “classical 3-point MACE” is defined as a composite of nonfatal stroke, nonfatal myocardial infarction, and cardiovascular death. But another study defines MACE as “CVD events, admission for HF (Heart Failure), ischemic cardiovascular [CV] events, cardiac death, or MACE”.
What is MACE criteria?
Component definitions of MACE included: AMI, acute coronary syndrome or ischemic heart disease (ACS/IHD), stroke (either ischemic or hemorrhagic stroke), revascularization procedures, cardiovascular (CV) death, and all-cause death.
What is the most common cause of ACS?
Acute coronary syndrome (ACS) is caused primarily by atherosclerosis. Most cases of ACS occur from disruption of a previously nonsevere lesion (an atherosclerotic lesion that was previously hemodynamically insignificant yet vulnerable to rupture).
What is the treatment for ACS?
Thrombolytics (clot busters) help dissolve a blood clot that’s blocking an artery. Nitroglycerin improves blood flow by temporarily widening blood vessels. Antiplatelet drugs help prevent blood clots from forming and include aspirin, clopidogrel (Plavix), prasugrel (Effient) and others.
What is the immediate treatment for ACS?
In the presence of ischaemic ECG changes or elevation of cardiac troponin, patients with an ACS should be treated immediately with both aspirin (300 mg loading dose) and ticagrelor (180 mg loading dose).
What is ACS risk?
ACS is a manifestation of CHD (coronary heart disease) and usually a result of plaque disruption in coronary arteries (atherosclerosis). The common risk factors for the disease are smoking, hypertension, diabetes, hyperlipidemia, male sex, physical inactivity, family obesity, and poor nutritional practices.
How do you prevent ACS?
Heart disease can lead directly to acute coronary syndrome, but those who do not have heart disease can protect themselves by practicing a healthy lifestyle: Following a heart-healthy diet: Eating a diet that includes fruits, vegetables, whole grains, and lean protein.
Why does ACS cause chest pain?
These potentially life-threatening conditions occur when a blockage causes blood flow to your heart to suddenly slow or stop. People with ACS can experience unstable angina or a heart attack (myocardial infarction). Common signs include chest pain or pressure (angina), shortness of breath (dyspnea) or dizziness.
What is MACE risk assessment?
Combined surgical and patient risk factors to predict. risk of major adverse cardiac events (MACE)* * MACE = ACS, MI, HF, unstable arrhythmia, death. Low risk.
What does 4P MACE include?
Abbreviations 3P-MACE: 3-point major adverse cardiovascular events; 4P-MACE: 4-point major adverse cardiovascular events; ACR: Albumin/creatinine ratio; AE: Adverse event; AESI: Adverse events of special interest; BI: Boehringer Ingelheim; BP: Blood pressure; BMI: Body mass index; CV: Cardiovascular; CG: Cockcroft-
What is MACE reduction?
Reduction of Major Adverse Cardiovascular Events (MACE) after Bariatric Surgery in Patients with Obesity and Cardiovascular Diseases: A Systematic Review and Meta-Analysis. Nutrients.
What is MACE in diabetes?
Abstract. Cardiovascular outcome trials (CVOTs) have demonstrated a significant reduction of major adverse cardiovascular events (MACE) in patients with type 2 diabetes (T2D) treated by SGLT-2 inhibitors. This holds true in the presence of background therapy with statins in most patients.
What does heart score stand for?
HEART is an acronym of its components: History, EKG, Age, Risk factors, and troponin. Each of these is scored with 0, 1 or 2 points. Designed to risk stratify patients with undifferentiated chest pain, not those already diagnosed with ACS.
What is CV event?
Abstract. Cardiovascular (CV) events or their minor syndromes, as various forms of ischemia, are medical emergencies that do not allow enough time for a guiding anamnesis or proper clinical examination, and lead to relying on Treatment Guidelines, but in many situations it is appropriate to deviate from them.
How do you identify MACE?
Background: The HEART score was developed to predict major adverse cardiac events (MACE) within 6 weeks in patients evaluated for chest pain. In the established score, age is scored as 65 y/o = 2 points.
Can stress cause ACS?
Acute psychological stress causes a number of physiologic responses that can trigger acute coronary syndromes in individuals with silent coronary artery disease.
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